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If you cut yourself and begin to bleed, the damaged tissues immediately release a chemical that initiates a chain reaction. Tiny disk-shaped platelets in your blood build up to form a plug at the injury site, and proteins in the blood plasma reinforce the clot by forming fibrous strands at the site. If a sample of blood is carefully removed from the blood vessel without allowing it to come in contact with the damaged tissue, and then the sample is placed on a smooth, plastic plate exposed to air, the blood will not clot. However, if a rough plastic plate or a glass plate is used instead, the blood will clot.
What helps cause blood to clot?

Explanation

The chemical response from the damaged tissue initiates the chain of responses that result in a blot clot that minimizes blood loss.

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